The incident occurred around 10:30 am and involved a twin-engine Cessna 421C, said Aviation Administration (FAA). Officials have not confirmed how many people were on board the aircraft.
In the videos shared on social media, a fire and a large plume of smoke is visible above the tree line in Fairview, along with apparent damage to a house in the neighborhood.
The aircraft also came down close to the smaller Troutdale Airport, known for flight training and recreational aviation.
According to Oregon Public Broadcasting reports, the aircraft broke into multiple parts after the crash. Currently, there has been no official information on injuries or fatalities.
Emergency responders, including Gresham Fire, The Port of Portland, Portland Fire and Rescue, and Clackamas Fire, participated in the response efforts.
Power outages have been also reported in the area.
The FAA and the National Transportation Safety Board will conduct an investigation into the crash.